Webb5 feb. 2015 · Conclusions. CLIPdb is a more complete and better-curated database focused on CLIP-seq data sets than those currently available, providing genome-wide, high-resolution binding sites. Characterizing the … Webb26 feb. 2007 · The database contains 292 motifs, and so the entire procedure yields a total of 291,000 motif P values. We measure the uniformity of these P values using quantile-quantile plots, an example of which is shown in Figure 3. The figure plots the computed null P values against the theoretically correct, uniform distribution (so-called 'rank P values').
Protein Patterns & Motifs
WebbThe 153-amino acid protein contains a RING finger domain. RT-PCR analysis detected highest levels of expression in liver and heart, moderate levels in placenta, lung, liver, kidney, pancreas, and lower levels in brain and skeletal muscle. Western blot analysis detected RNF181 protein in human platelets as a 36-kD dimer and an 18-kD monomer. WebbRNA binding motif protein 3 (RBM3) is a member of the highly conserved RNA binding proteins that participate in cellular processes by binding to mRNA of target genes. 26 Moreover, it acts as a cold shock response protein to protect cells from hypothermia-induced death. 27 Under normal physiological conditions, RBM3 is essential for cell … molly rose and steven a smith
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WebbEach residue must be separated by - (minus). x represents any amino acid. [DE] means either D or E. {FWY} means any amino acid except for F, W and Y. A (2,3) means that A … Webb21 sep. 2024 · Sequence motif searches can be run for protein, DNA, or RNA sequences. Select the type of query sequence using the Sequence Type options. The actual … Webb3 apr. 2024 · For instance, the HOCOMOCO database (v11) stores di-PWMs of binding motifs of Human and Mouse transcription factors (292 and 257, respectively), which were directly computed from experimental ChIP-Seq data (Kulakovskiy et al. 2024).For detecting new binding sites, it was shown that di-PWMs provide enhance sensitivity compared to … molly rose avocat